Small Molecule Modulators of the Androgen Receptor

This technology describes compounds useful for modulating the activity of an androgen receptor, or a variant thereof, and related compositions and methods. Compounds of the invention are useful for antagonizing the androgen receptor splice variant AR-v7, and for the treatment of castration-resistant prostate cancer.

Researchers

Angela Koehler / Nicholas Struntz / David Freeman / Shelby Doyle / Andre Richters

Departments: Department of Biological Engineering
Technology Areas: Biotechnology: Biomanufacturing, Biomedical Devices & Systems / Therapeutics: Cell Based Therapy

  • small molecule modulators of the androgen receptor
    United States of America | Granted | 10,961,216

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