A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

A drug delivery system is provided for treatment of oxidative stress. The drug delivery system can include a therapeutic agent and a matrix. The therapeutic agent can include an antioxidant or steroid. The matrix can include a hydrogel, particle, microparticle, or nanoparticle. A method of treating injury, including peripheral nerve injury or spinal cord injury, is also provided. The method includes injecting the drug delivery system at the site of injury.

Researchers

Eric Woodard / Christopher Pritchard / Daniel Siegwart / Timothy O'Shea / Francis Reynolds / Jonathan Slotkin / Robert Langer / Daniel Anderson

Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems / Chemicals & Materials: Composites, Polymers / Therapeutics: Regenerative Medicine
Impact Areas: Healthy Living

  • a novel injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate
    Japan | Published application

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