In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1
Invention type: Technology
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Case number: #20746
Provided herein are engineered HSV-1 vectors comprising a modified HSV-1 genome. The engineered HSV-1 vectors can be used to deliver genetic circuits (e.g., up to 100 kb) to cells in vitro or in vivo. Methods of treating or diagnosing a disease (e.g., cancer) using the engineered HSV-1 vectors described herein are also provided.
Researchers
Ron Weiss
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Maria Hottelet Foley
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Jin Huh
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Ross Jones
Departments: Department of Biological Engineering
Technology Areas: Diagnostics: Assays / Drug Delivery: Vectors & Virus like Particles
Impact Areas: Healthy Living
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engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof
United States of America | Published application | 0 -
engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof
China | Published application -
engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof
European Patent Convention | Published application -
engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof
Japan | Published application -
engineered herpes simplex virus-1 (hsv-1) vectors and uses thereof
Hong Kong | Published application
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