Novel Method to Correct Altered Synaptic Signaling in Autism and Intellectual Disability
Invention type: Technology
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Case number: #18383PHJ
Disclosed herein are novel methodologies of treating fragile X syndrome and related disorders by inhibiting mGlu5-relevant signaling pathways via the reduction of β-arrestin2 protein levels or the diminution of mGlu5 and β-arrestin2 protein interactions.
Researchers
Mark Bear
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Benjamin Auerbach
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Laura Stoppel
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Robert Lefkowitz
Departments: Department of Brain and Cognitive Sciences
Technology Areas: Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living
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methods of treating fragile x syndrome and related disorders
United States of America | Granted | 10,682,397
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