Method to Simulate Metrics of Vascular Function from Clinical Data

A method includes determining, by a computer processor coupled to memory, data associated with a patient, the data comprising a heart rate value, a peak velocity through aortic valve value, and a stroke volume value; generating  a flow waveform for the patient using the data; determining a set of candidate vascular impedance (VI) values for the patient based at least in part on the flow waveform, the set of candidate VI values comprising first and second VI values; determining a first pressure waveform using the flow waveform and the first VI value; determining a second pressure waveform using the flow waveform and the second VI value; determining a blood pressure value for the patient; determining that the first pressure waveform is a closer match to the blood pressure value than the second pressure waveform; and determining that the patient has a vascular impedance of the first VI value.