Disrupted in Schizophrenia 1 (DISC-1) Interacts with the Wnt Signaling Pathway and Regulates Neurogenesis

The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.

Researchers

Li-Huei Tsai / Stephen Haggarty / Yingwei Mao / Jon Madison

Departments: DLC Heads Science
Technology Areas: Chemicals & Materials: Catalysis & Synthesis / Computer Science: Bioinformatics / Sensing & Imaging: Chemical & Radiation Sensing
Impact Areas: Healthy Living

  • disc-1 pathway activators in the control of neurogenesis
    United States of America | Granted | 8,263,547
  • disc-1 pathway activators in the control of neurogenesis
    United States of America | Granted | 10,124,035

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